Bio::Prospect::SoapServer - execute Prospect locally


Bio-Prospect documentation Contained in the Bio-Prospect distribution.

Index


Code Index:

NAME

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 Bio::Prospect::SoapServer -- execute Prospect locally
 $Id: SoapServer.pm,v 1.10 2003/11/18 19:45:45 rkh Exp $

SYNOPSIS

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 use Bio::Prospect::SoapServer;
 use Bio::Prospect::Options;
 my $p2options = new Bio::Prospect::Options;
 my $p2factory = new Bio::Prospect::SoapServer( {options=>$p2options} );
 my $xmlout = $p2factory->thread( $sequence );

DESCRIPTION

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Bio::Prospect::SoapServer is runs Prospect remotely using SOAP as the protocol. Utilize a LocalClient object to actually run Prospect.

ROUTINES & METHODS

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thread_summary()

 Name:      thread_summary()
 Purpose:   thread a sequence using Bio::Prospect::LocalClient
 Arguments: comma-separated list:
    0 - string containing sequence id
    1 - string, contains protein sequence (or '' if secondary structure is
        defined in #2)
    2 - string, contains secondary structure information in phd format
        (or '' if sequence is defined in #1)
    3 - string, one of 'scop', 'fssp', 'all' (or '' if templates is defined in #4)
        to define a template set
    4 - string, contains a space-separated list of templates (or '' if
        template set is defined in #3)
    5 - string, one of 'global' or 'global_local' for alignment type
    6 - string, either '0' (false) or '1' (true) for calculating zscores
 Returns:   XML string containing prospect results

thread()

 Name:      xml()
 Purpose:   thread a sequence using Bio::Prospect::LocalClient
 Arguments: comma-separated list:
    0 - string containing sequence id
    1 - string, contains protein sequence (or '' if secondary structure is
        defined in #2)
    2 - string, contains secondary structure information in phd format
        (or '' if sequence is defined in #1)
    3 - string, one of 'scop', 'fssp', 'all' (or '' if templates is defined in #4)
        to define a template set
    4 - string, contains a space-separated list of templates (or '' if
        template set is defined in #3)
    5 - string, one of 'global' or 'global_local' for alignment type
    6 - string, either '0' (false) or '1' (true) for calculating zscores
 Returns:   XML string containing prospect results

ping()

 Name:      ping()
 Purpose:   return whether alive or not
 Arguments: none
 Returns:   0 - dead, 1 - alive

INTERNAL METHODS & ROUTINES

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The following functions are documented for developers' benefit. THESE SHOULD NOT BE CALLED OUTSIDE OF THIS MODULE. YOU'VE BEEN WARNED.

_parseOption()

 Name:      _parseOption()
 Purpose:   parse arguments to the thread, thread_summary, and xml() methods
 Arguments: comma-separated list:
    1 - string, one of 'scop', 'fssp', 'all' (or '' if templates is defined in #4)
        to define a template set
    2 - string, contains a space-separated list of templates (or '' if
        template set is defined in #3)
    3 - string, one of 'global' or 'global_local' for alignment type
    4 - string, either '0' (false) or '1' (true) for calculating zscores
 Returns:   Bio::Prospect::Options object


Bio-Prospect documentation Contained in the Bio-Prospect distribution.

package Bio::Prospect::SoapServer;

use base Bio::Prospect::Client;

use warnings;
use strict;
use Data::Dumper;
use Bio::Prospect::Exceptions;
use Bio::Prospect::LocalClient;
use Bio::Prospect::Options;
use Bio::Seq;
use SOAP::Lite;

use vars qw( $VERSION );
$VERSION = sprintf( "%d.%02d", q$Revision: 1.10 $ =~ /(\d+)\.(\d+)/ );


sub new() {
  my $type = shift;
  my $self = {};
  return (bless $self,$type);
}


#-------------------------------------------------------------------------------
# thread_summary()
#-------------------------------------------------------------------------------

sub thread_summary($$) {
  my ($self,$seqID,$s,$secondaryStructure,$templateSet,$templates,$alignmentType,$calculateZscores) = @_;

  my $opts = &_parseOptions($templateSet,$templates,$alignmentType,$calculateZscores);

  # use LocalClient to do the work
  my $LocalClient = new Bio::Prospect::LocalClient( {options=>$opts} );
  my $seq = new Bio::Seq( -display_id => $seqID, -seq => $s );
  my @threads = $LocalClient->thread_summary( $seq );

  return( \@threads );
}


#-------------------------------------------------------------------------------
# xml()
#-------------------------------------------------------------------------------

sub xml($$) {
  my ($self,$seqID,$s,$secondaryStructure,$templateSet,$templates,$alignmentType,$calculateZscores) = @_;

  my $opts = &_parseOptions($templateSet,$templates,$alignmentType,$calculateZscores);

  # use LocalClient to do the work
  my $LocalClient = new Bio::Prospect::LocalClient( {options=>$opts} );
  my $seq = new Bio::Seq( -display_id => $seqID, -seq => $s );
  my $xml = $LocalClient->xml( $seq );

  return( $xml );
}


#-------------------------------------------------------------------------------
# ping()
#-------------------------------------------------------------------------------

sub ping {
  return 1;
}


#-------------------------------------------------------------------------------
# INTERNAL METHODS: not intended for use outside this module
#-------------------------------------------------------------------------------

#-------------------------------------------------------------------------------
# _parseOption()
#-------------------------------------------------------------------------------

sub _parseOptions {
  my ($templateSet,$templates,$alignmentType,$calculateZscores) = @_;

  # build Bio::Prospect::Options.  howto handle caching???
  my $opts = new Bio::Prospect::Options;

  $opts->{'templates'} = [ split /,/,$templates ] if defined $templates;
  $opts->{'zscore'} = $calculateZscores if defined $calculateZscores;
  $opts->{'global_local'} = ( defined $alignmentType ) ?  $alignmentType : '-global';
  $opts->{'svm'} = 1;
  $opts->{'seq'} = 1;

  return( $opts );
}


1;