Bio::DB::InMemoryCache - Abstract interface for a sequence database


BioPerl documentation Contained in the BioPerl distribution.

Index


Code Index:

NAME

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Bio::DB::InMemoryCache - Abstract interface for a sequence database

SYNOPSIS

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  $cachedb = Bio::DB::InMemoryCache->new( -seqdb => $real_db,
                                          -number => 1000);
  #
  # get a database object somehow using a concrete class
  #

  $seq = $cachedb->get_Seq_by_id('ROA1_HUMAN');

  #
  # $seq is a Bio::Seq object
  #

DESCRIPTION

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This is a memory cache system which saves the objects returned by Bio::DB::RandomAccessI in memory to a hard limit of sequences.

CONTACT

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Ewan Birney <birney@ebi.ac.uk>

Support

Please direct usage questions or support issues to the mailing list:

bioperl-l@bioperl.org

rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address it. Please include a thorough description of the problem with code and data examples if at all possible.

Reporting Bugs

Report bugs to the Bioperl bug tracking system to help us keep track the bugs and their resolution. Bug reports can be submitted via the web:

  https://redmine.open-bio.org/projects/bioperl/

APPENDIX

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The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _

get_Seq_by_id

 Title   : get_Seq_by_id
 Usage   : $seq = $db->get_Seq_by_id('ROA1_HUMAN')
 Function: Gets a Bio::Seq object by its name
 Returns : a Bio::Seq object
 Args    : the id (as a string) of a sequence
 Throws  : "id does not exist" exception

get_Seq_by_acc

 Title   : get_Seq_by_acc
 Usage   : $seq = $db->get_Seq_by_acc('X77802');
 Function: Gets a Bio::Seq object by accession number
 Returns : A Bio::Seq object
 Args    : accession number (as a string)
 Throws  : "acc does not exist" exception

get_Seq_by_version

 Title   : get_Seq_by_version
 Usage   : $seq = $db->get_Seq_by_version('X77802.1');
 Function: Gets a Bio::Seq object by sequence version
 Returns : A Bio::Seq object
 Args    : accession.version (as a string)
 Throws  : "acc.version does not exist" exception


BioPerl documentation Contained in the BioPerl distribution.
#
# BioPerl module for Bio::DB::InMemoryCache
#
# Please direct questions and support issues to <bioperl-l@bioperl.org> 
#
# Cared for by Ewan Birney <birney@sanger.ac.uk>
#
# Copyright Ewan Birney
#
# You may distribute this module under the same terms as perl itself
#
# POD documentation - main docs before the code


# Let the code begin...

package Bio::DB::InMemoryCache;


use strict;

use Bio::Seq;

use base qw(Bio::Root::Root Bio::DB::SeqI);

sub new {
    my ($class,@args) = @_;

    my $self = Bio::Root::Root->new();
    bless $self,$class;

    my ($seqdb,$number,$agr) =
		$self->_rearrange([qw(SEQDB NUMBER AGRESSION)],@args);

    if( !defined $seqdb || !ref $seqdb ||
		  !$seqdb->isa('Bio::DB::RandomAccessI') ) {
       $self->throw("Must be a RandomAccess database not a [$seqdb]");
    }

    if( !defined $number ) {
        $number = 1000;
    }

    $self->seqdb($seqdb);
    $self->number($number);
    $self->agr($agr);

    # we consider acc as the primary id here
    $self->{'_cache_number_hash'} = {};
    $self->{'_cache_id_hash'}     = {};
    $self->{'_cache_acc_hash'}    = {};
    $self->{'_cache_number'}      = 1;

    return $self;
}

sub get_Seq_by_id{
   my ($self,$id) = @_;

   if( defined $self->{'_cache_id_hash'}->{$id} ) {
		my $acc = $self->{'_cache_id_hash'}->{$id};
		my $seq = $self->{'_cache_acc_hash'}->{$acc};
		$self->{'_cache_number_hash'}->{$seq->accession} =
		  $self->{'_cache_number'}++;
		return $seq;
   } else {
		return $self->_load_Seq('id',$id);
   }
}

sub get_Seq_by_acc{
   my ($self,$acc) = @_;

   #print STDERR "In cache get for $acc\n";
   if( defined $self->{'_cache_acc_hash'}->{$acc} ) {
       #print STDERR "Returning cached $acc\n";
       my $seq = $self->{'_cache_acc_hash'}->{$acc};
       $self->{'_cache_number_hash'}->{$seq->accession} =
			$self->{'_cache_number'}++;
       return $seq;
   } else {
     return $self->_load_Seq('acc',$acc);
   }
}



sub number {
    my ($self, $number) = @_;
    if ($number) {
        $self->{'number'} = $number;
    } else {
        return $self->{'number'};
    }
}

sub seqdb {
    my ($self, $seqdb) = @_;
    if ($seqdb) {
        $self->{'seqdb'} = $seqdb;
    } else {
        return $self->{'seqdb'};
    }
}

sub agr {
    my ($self, $agr) = @_;
    if ($agr) {
        $self->{'agr'} = $agr;
    } else {
        return $self->{'agr'};
    }
}


sub _load_Seq {
  my ($self,$type,$id) = @_;

  my $seq;

  if( $type eq 'id') {
    $seq = $self->seqdb->get_Seq_by_id($id);
  }elsif ( $type eq 'acc' ) {
    $seq = $self->seqdb->get_Seq_by_acc($id);
  } else {
    $self->throw("Bad internal error. Don't understand $type");
  }
  if( ! $seq ) {
      # warding off bug #1628
      $self->debug("could not find seq $id in seqdb\n");
      return;
  }

  if( $self->agr() ) {
      #print STDERR "Pulling out into memory\n";
      my $newseq = Bio::Seq->new( -display_id => $seq->display_id,
				  -accession_number  => $seq->accession,
				  -seq        => $seq->seq,
				  -desc       => $seq->desc,
				  );
      if( $self->agr() == 1 ) {
	  foreach my $sf ( $seq->top_SeqFeatures() ) {
	      $newseq->add_SeqFeature($sf);
	  }

	  $newseq->annotation($seq->annotation);
      }
      $seq = $newseq;
  }

  if( $self->_number_free < 1 ) {
    # remove the latest thing from the hash
    my @accs = sort { $self->{'_cache_number_hash'}->{$a} <=>
								$self->{'_cache_number_hash'}->{$b} }
                          keys %{$self->{'_cache_number_hash'}};

    my $acc = shift @accs;
    # remove this guy
    my $seq = $self->{'_cache_acc_hash'}->{$acc};

    delete $self->{'_cache_number_hash'}->{$acc};
    delete $self->{'_cache_id_hash'}->{$seq->id};
    delete $self->{'_cache_acc_hash'}->{$acc};
  }

  # up the number, register this sequence into the hash.
  $self->{'_cache_id_hash'}->{$seq->id} = $seq->accession;
  $self->{'_cache_acc_hash'}->{$seq->accession} = $seq;
  $self->{'_cache_number_hash'}->{$seq->accession} = $self->{'_cache_number'}++;

  return $seq;
}


sub _number_free {
  my $self = shift;

  return $self->number - scalar(keys %{$self->{'_cache_number_hash'}});
}

sub get_Seq_by_version{
   my ($self,@args) = @_;
   $self->throw("Not implemented it");
}

## End of Package

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